• How Pictures Of Infant Boy's Eyes Helped Diagnose Cancer

    by Joe Palca More

    Photographic Detection of Retinoblastoma

     

  • A New Molecular Mechanism for Sporadic ALS?

    Shi et al. J. Am. Chem. Soc., More

    A New Molecular Mechanism for Sporadic ALS?

     

  • What Does the Mystery of "Gel Shifting" during SDS-PAGE Tell Us About Interaction between Proteins and Surfactants?

    Protein Science, 2012, 21(8): 1197-209 More

    What Does the Mystery of "Gel Shifting" during SDS-PAGE Tell Us about Interaction between Proteins and Surfactants?

     

  • Using "Protein Charge Ladders" to measure the net Electrostatic Charge of Misfolded Proteins

    Shi, Mowery and Shaw; J. Mol. Bio., 2013 More

    Using "Protein Charge Ladders" to Measure the Net Electrostatic Charge of Misfolded Proteins

  • Quantifying the Effect of Metal Binding on the Net Charge of Neurotoxic Proteins

    Shi, Mowery and Shaw; J. Mol. Bio., 2013 More

    Quantifying the Effect of Metal Binding on the Net Charge of Neurotoxic Proteins

  • Using Three Dimensional Printing to Teach Protein Allostery to Visually Impaired Students

    Educational Outreach at Dallas ISD

    Using Three Dimensional Printing to Teach Protein Allostery to Visually Impaired Students

  • Using Three Dimensional Printing to Teach Protein Allostery to Visually Impaired Students

    Educational Outreach at Dallas ISD

    Using Three Dimensional Printing to Teach Protein Allostery to Visually Impaired Students

About Us

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Research in the Shaw Laboratory occurs at the crossroads of chemistry, structural biology, proteomics and biophysics. One of our primary aims is to understand how changes in the electrostatic properties of a protein can accelerate its aggregation. The aggregation of certain proteins can cause human diseases such as amyotrophic lateral sclerosis. We intend to apply our work in protein biophysics and protein chemistry towards the development of new classes of small molecules that can inhibit the aggregation of proteins. Visit us at the lab's website to learn more about our research!

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Congratulations to Dr. Shaw for winning an NSF CAREER award—and on his first try too! The award will fund our research from 2014 through 2019.

We are working to develop new therapies to treat the devastating neurodegenerative disease, amyotrophic lateral sclerosis (ALS) and we thank the DOD and CDMRP for funding our research!

Congratulations to Dr. Shaw for recently winning his second NIH LRP award (this time from the NEI) for his work on the photographic detection of retinoblastoma!

The Shaw Research Group

  • Department of Chemistry&Biochemistry
  • 101 Bagby Avenue, Waco Texas
  • Phone: +1 (254) 710-2004
  • Fax: +1 (254) 710-4272
  • E-mail: info@shawlaboratory.com