Alonzo, E. A.; Lato, T. J.; Gonzalez, M.; Olson, T. L.; Savage, Q. R.; Garza, L. N.; Green, M. T.; Koone, J. C.; Cook, N. E.; Dashnaw, C. M.; Armstrong, D. B., Wood, J. L.; Garbrecht, L. S.; Haynes, M. L.; Jacobson, M. R.; Guberman-Pfeffer, M. J.; Minkara, M. S.; Wedler, H. B.; Zechmann, B.; Shaw, B. F. Universal pictures: A lithophane codex helps teenagers with blindness visualize nanoscopic systems, Science Advances10, 2, (2024).


Koone, J. C.; Simmang, M.; Saenger, D. L.; Hunsicker-Wang, L. M.; Shaw, B. F. Charge Regulation in a Rieske Proton Pump Pinpoints Zero, One, and Two Proton-Coupled Electron Transfer. J Am Chem Soc 2023, 145 (30), 16488-16497.

Zhang, A. Y.; Dashnaw, C. M.; Gonzalez, M.; Koone, J. C.; Wells, N. A.; Smith, C. A.; Guberman-Pfeffer, M. J.; Shaw, B. F. Oxidation of Dueling Cysteine Promotes Subunit Exchange in SOD1. ACS Chem Neurosci 2023. DOI: 10.1021/acschemneuro.3c00174.


Koone, J. C.; Dashnaw, C. M.; Gonzalez M.; Shaw, B.F., A method for quantifying how the activity of an enzyme is affected by the net charge of its nearest crowded neighbor. Protein Science 2022, 31(9), e4384.

Koone, J. C.; Dashnaw, C. M.; Alonzo, E. A.; Iglesias, M. A.; Patero, K.-S.; Lopez, J. J.; Zhang, A. Y.; Zechmann, B.; Cook, N. E.; Minkara, M. S.; Supalo, C. A.; Wedler, H. B.; Guberman-Pfeffer, M. J.; Shaw, B. F., Data for all: Tactile graphics that light up with picture-perfect resolution. Science Advances 2022, 8 (33), eabq2640.

Dashnaw C.M., Zhang AY, Gonzalez M., Koone J.C., Shaw B.F., Metal migration and subunit swapping in als-linked sod1: Zn(2+) transfer between mutant and wild-type occurs faster than the rate of heterodimerization. J Biol. Chem. 2022, 298(12):102610.


Baumer, K.M., Cook, C.D., Zahler, C.T., Beard, A.A., Chen, Z., Koone, J.C., Dashnaw, C.M., Villacob, R.A., Solouki, T., Wood, J.L., Borchelt, D.R., Shaw, B.F. Supercharging Prions via amyloid-selective lysine acetylation.  Angew. Chem. Int. Ed. 2021, 60 (27), 15069-15079.

Baumer, K.M., Lopez, J.J., Naidu, S.V., Rajendran, S., Iglesias, M.A., Carleton, K.M., Eisenmann, C.J., Carter, L.R., Shaw, B.F. Visualizing 3D imagery by using candy-like models. Sci. Adv. 2021, 7 (22), eabh0691.

Dashnaw, C.M., Koone, J.C., Abdolvahabi, A. Shaw, B.F. Measuring how two proteins affect each other’s net charge in a crowded environment. Protein Sci 2021.


Zhang, A. Y.; Koone, J. C.; Dashnaw, C. M.; Zahler, C. T.; Shaw, B. F. Complete Charge Regulation by a Redox Enzyme Upon Single Electron Transfer. Angew. Chem. Int. Ed. 2020, 59 (27), 10989–10995.

Baumer, K. M.; Koone, J. C.; Shaw, B. F. Kinetic Variability in Seeded Formation of ALS-Linked SOD1 Fibrils Across Multiple Generations. ACS Chem. Neurosci. 2020, 11 (3), 304–313.


Munson, M. C.; Plewman, D. L.; Baumer, K. M.; Henning, R.; Zahler, C. T.; Kietzman, A. T.; Beard, A. A.; Mukai, S.; Diller, L.; Hamerly, G.; Shaw, B. F. Autonomous Early Detection of Eye Disease in Childhood Photographs. Sci. Adv. 2019, 5 (10), eaax6363.

Zahler, C. T.; Shaw, B. F. What Are We Missing by Not Measuring the Net Charge of Proteins? Chem. Euro. J. 2019, 25 (32), 7581–7590.


Rasouli, S.; Abdolvahabi, A.; Croom, C. M.; Plewman, D. L.; Shi, Y.; Shaw, B. F. Glycerolipid Headgroups Control Rate and Mechanism of Superoxide Dismutase-1 Aggregation and Accelerate Fibrillization of Slowly Aggregating Amyotrophic Lateral Sclerosis Mutants. ACS Chem. Neurosci. 2018, 9 (7), 1743–1756.

Zahler, C. T.; Zhou, H.; Abdolvahabi, A.; Holden, R. L.; Rasouli, S.; Tao, P.; Shaw, B. F. Direct Measurement of Charge Regulation in Metalloprotein Electron Transfer. Angew. Chem. Int. Ed. 2018, 57 (19), 5364–5368.


Rasouli, S.; Abdolvahabi, A.; Croom, C. M.; Plewman, D. L.; Shi, Y.; Ayers, J. I.; Shaw, B. F. Lysine Acylation in Superoxide Dismutase-1 Electrostatically Inhibits Formation of Fibrils with Prion-like Seeding. J. Biol. Chem. 2017, 292 (47), 19366–19380.

Abdolvahabi A, Shi Y, Rasouli S, Croom CM, Chuprin A, Shaw BF. How Do Gyrating Beads Accelerate Amyloid Fibrillization? Biophys J. 2017 Jan 24;112(2):250-264.


Shi, Y., Acerson, M.J., Abdolvahabi, A, Mowery, R.A., Shaw B.F. Gibbs energy of superoxide dismutase heterodimerization accounts for variable survival in amyotrophic lateral sclerosis. J Am Chem Soc. 2016 Apr 27;138(16):5351-62

Abdolvahabi A, Shi Y, Chuprin A, Rasouli S, Shaw BF. Stochastic formation of fibrillar and amorphous superoxide dismutase oligomers linked to amyotrophic lateral sclerosi. ACS Chem Neurosci. 2016 Jun 15;7(6):799-810


Shi, Y., Acerson, M. J., Shuford, K. L. & Shaw, B. F. Voltage induced misfolding of zinc replete ALS mutant superoxide dismutase-1. ACS Chem. Neurosci., 2015, Oct 21;6(10):1696-707

Sea, K.; Sohn, S. H.; Durazo, A.; Sheng, Y.; Shaw, B. F.; Cao, X.; Taylor, A. B.; Whitson, L. J.; Holloway, S. P.; Hart, P. J.; Cabelli, D. E.; Gralla, E. B.; Valentine, J. S. Insights into the role of the unusual disulfide bond in copper-zinc superoxide dismutase. J. Biol. Chem., 2015, 290, 2405-2418.

Abdolvahabi, A.; Shi, Y.; Rhodes, N. R.; Cook, N. P.; Marti, A. A.; Shaw, B. F. Arresting Amyloid with Coulomb’s Law: Acetylation of ALS-Linked SOD1 by Aspirin Impedes Aggregation. Biophys J. 2015, 108, 1199-212.


Abdolvahabi, A., Gober, J. L., Mowery, R. A., Shi, Y. & Shaw, B. F. Metal Ion-Specific Screening of Charge Effects in Protein Amide H/D Exchange Follows the Hofmeister Series. Anal Chem. 2014,86, 10303-10.

Rivas-Perea, P., Baker, E., Hamerly, G. & Shaw, B. F. Detection of leukocoria using a soft fusion of expert classifiers under non-clinical settings. BMC Ophthalmol. 2014; 14, 110.

Shi, Y., Abdolvahabi, A. & Shaw, B. F. Protein charge ladders reveal that the net charge of ALS-linked superoxide dismutase can be different in sign and magnitude from predicted values. Protein Sci. 2014, [Epub ahead of print].


7) Shi Y, Rhodes NR, Abdolvahabi A, Kohn T, Cook NP, Marti AA, Shaw BF. Deamidation of Asparagine to Aspartate Destabilizes Cu, Zn Superoxide Dismutase, Accelerates Fibrillization, and Mirrors ALS-Linked Mutations. J Am Chem Soc. 2013;135(42):15897-908.

Abdolvahabi, A., Taylor B.W., Holden R.L., Shaw E.V., Kentsis A., Rodriguez-Galindo C., Mukai S., Shaw, B.F. Colorimetric and Longitudinal Analysis of Leukocoria in Recreational Photographs of Children with Retinoblastoma. PLoS ONE. 2013

Shi Y, Mowery RA, Shaw BF. Effect of Metal Loading and Subcellular pH on Net Charge of Superoxide Dismutase-1. J. Mol. Biol. 2013;425(22):4388-404

Alves, N.J., Champion, M.M., Stefanick, J.F., Handlogten, M.W., Moustakas, D.T., Shi, Y., Shaw, B.F., Navari, R.M., Kiziltepe, T., Bilgicer, B. Selective photocrosslinking of functional ligands to antibodies via the conserved nucleotide binding site. Biomaterials. 2013; 34(22): 5700-5710.

Krishnamurthy, V.J., Raman, V.S., Mowery, R.A., Hentz, M., Balega, J.D., Shaw, B.F., Kumar, K. Ligand-Induced Protein Mobility in Complexes of Carbonic Anhydrase II and Benzenesulfonamides with Oligoglycine Chains. PLoS ONE. 2013; 8(3): e57629.


Shi Y., Mowery R.A., Ashley J., Hentz M., Ramirez A.J., Bilgicer B., Slunt-Brown H., Borchelt D.R., Shaw B.F.* Abnormal SDS-PAGE migration of cytosolic proteins can identify domains and mechanisms that control surfactant binding. Protein Sci. 2012; 21(8):1197-1209.

Shaw, B.F.*, Schneider, G.F., Whitesides, G.M.* Effect of Surfactant Hydrophobicity on the Pathway for Unfolding of Ubiquitin J. Am. Chem. Soc. 2012; 134(45):18739-18745.
(*BFS co-corresponding author with George M. Whitesides)


Shaw, B.F.*, Schneider, G.F., Arthanari, H., Narovlyansky, M., Moustakas, D., Durazo, A., Wagner, G., Whitesides, G.M.* Complexes of native Ubiquitin and dodecyl sulfate illustrate the nature of hydrophobic and electrostatic interactions in the binding of proteins and surfactants. J. Am. Chem. Soc. 2011; 133(44): 17681-17695.
(*BFS co-corresponding author with George M. Whitesides)


Shaw, B.F.*, Arthanari, H., Lee, A., Durazo, A., Frueh, D.P., Pollastri, M.P., Bilgicer, B., Gygi, S.P., Wagner, G., Whitesides, G.M.* Neutralizing positive charges at the surface of a protein lowers its rate of amide H/D exchange without altering its structure or raising its thermostability. J. Am. Chem. Soc. 2010; 132 (49): 17411-17425. (*BFS co-corresponding author with George M. Whitesides)


Bilgicer, B., Thomas, S.W., Shaw, B.F., Kaufman, G.K., Krishnamurthy, V.M., Estroff, L.A., Whitesides, G.M. A non-chromatographic method for the purification of a bivalent monoclonal IgG antibody from biological fluid. J. Am. Chem. Soc. 2009; 131(26): 9361-7.

Durazo, A., Shaw, B.F., Chattopadhyay, M., Faull, K.F., Valentine, J.S., Whitelegge, J.P. Metal free wild-type superoxide dismutase-1 and three different ALS variants share a similar partially unfolded β-barrel at physiological temperature. J. Biol. Chem. 2009; 284(49): 34382-9.

Kaufman, G.K., Thomas, S.W., Reches, M., Feng, J., Shaw, B.F., Whitesides, G.M. Phase separation of 2D Coulombic crystals of meso-scale dipolar particles from meso-scale polarizable “solvent.” App. Phys. Lett. 2009; 94 (4): 44102.

Kaufman, G.K., Thomas, S.W., Reches, M., Shaw, B.F., Feng, J., Whitesides, G.M. Phase separation of 2D meso-scale Coulombic crystals from meso-scale polarizable “solvent.” Soft Matter 2009; 5: 1188-1191.

Durer, Z., Cohlberg, J.A., Dinh, P., Padua, S., Ehrenclou, K., Downes, S., Tan, J.K., Nakano, Y., Bowman, C.J., Rosales, J., Hoskins, J.L., Kwon, C., Mason, A.Z., Rodriguez, J.A., Doucette, P.A., Shaw, B.F., Valentine, J.S. Loss of metal ions, disulfide reduction and mutations related to familial ALS promote amyloid formation from superoxide dismutase. PLoS ONE 2009; 4(3): e5004.


Shaw, B.F., Schneider, G.F., Bilgicer, B., Kaufman, G.K., Neveu, J.M., Lane, W.S., Whitelegge, J.P., Whitesides, G.M. Lysine acetylation can generate highly charged enzymes with increased resistance towards irreversible inactivation. Protein Sci. 2008; 17(8): 1446-1455.